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In this study, the final SVM diagnostic model was constructed using the 19 genes selected by LASSO regression, rather than only the five top-ranked genes

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Disruption of the antigen processing machinery (APM) IGF-1 consistently downregulated TAP1, TAP2, ERAP1, and 2-microglobulin (2M)key components required for peptide transport and loading onto MHC-I complexes

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